Stomach Cancer Treatment Options in Portland & Vancouver

There are a number of treatments available for stomach (gastric) cancer, a type of gastrointestinal cancer. Your GI cancer doctor will review your specific diagnosis and create a treatment plan that's best for you. In many cases, several treatments are part of the overall plan.

gastric cancer patient with oncologist

Who Treats Stomach Cancer? 

Your care team will usually include a cancer surgeon, a medical oncologist, and a radiation oncologist. Additionally, the gastroenterologist who may have diagnosed you is included in the team. We encourage most gastric cancer patients to meet with both the medical oncologist and surgeon before beginning treatment to discuss their options and the timing of treatments, including surgery.

Our team of GI cancer specialists offers the most advanced and comprehensive options for treating GI cancers, including access to clinical trials, in the Portland and Vancouver metro area.

Determining Treatment for Stomach Cancer Based on Stage

Along with staging the cancer, doctors determine the best treatment options by categorizing stomach cancers into larger groups. These include:

Very early-stage cancers

Cancer is present but has not spread past the stomach's inner lining.

Potentially resectable cancers

These cancers have penetrated the stomach wall, and nearby areas or lymph nodes could also be affected. Surgery to attempt complete removal (resection) may be a suitable option.

Unresectable local or regional cancers

These cancers have also penetrated the stomach wall and may affect areas nearby or lymph nodes. A complete resection is unlikely at this point, even though the cancer hasn't reached distant parts of the body.

Metastatic cancers

These cancers have spread to distant parts of the body.

Stomach Cancer Treatments

The main treatment options for stomach cancer include: 

Surgery for Resectable Stomach Cancer

Most stomach cancer treatment plans include surgery, especially if the cancer was caught at an early stage. Surgery can be performed for two main reasons:

  • To remove the cancer. This may involve removing part or all of the stomach. Removing some nearby lymph nodes or other structures may also be necessary.
  • To relieve symptoms. Surgery may be used to prevent or alleviate symptoms caused by cancer rather than to provide a cure. This is known as palliative surgery.

The type and stage of stomach cancer will influence whether surgery is an option and, if so, which method is best.

Surgical Procedures Used to Remove Stomach Cancer

Endoscopic Resection

This removes the tumor and some layers of the stomach wall using an endoscope, which is inserted through the throat instead of making an incision. Endoscopic resection includes endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD).

Gastrectomy

A gastrectomy procedure removes part or all of the stomach:

  • Subtotal (partial) gastrectomy: This removes the part of the stomach containing cancer, nearby lymph nodes, and other tissues and organs near the tumor. The spleen may also be removed.
  • Total gastrectomy: This procedure removes the entire stomach, nearby lymph nodes, and parts of the esophagus, small intestine, and other tissues near the tumor. The spleen may also be removed. The end of the esophagus is then attached to part of the small intestine so the patient can continue to eat and swallow.

Most subtotal and total gastrectomies are performed through a large incision in the abdomen. In some cases, the surgeon may attempt a laparoscopic approach instead.

Palliative Surgery for Unresectable Stomach Cancer

If your stomach cancer cannot be completely removed, surgery to help control the cancer or alleviate symptoms will likely be recommended. This may include:

  • Gastrojejunostomy: The cancerous section of the stomach blocking the opening into the small intestine is removed, and the stomach is connected to the jejunum (a part of the small intestine) to allow food and medicine to pass through.
  • Feeding tube placement: A minor operation can be performed to insert a feeding tube through the skin of the abdomen into the lower part of the stomach. This helps those who cannot receive adequate nutrition due to the effects of cancer.
  • Upper endoscopy: Endoscopic tumor ablation, which uses a laser to vaporize the tumor, or stent placement to keep a tumor from blocking the opening at the beginning or end of the stomach, are two procedures that can help relieve symptoms. 

Chemotherapy for Stomach Cancer

Chemotherapy uses drugs to stop the growth of cancer cells by killing or preventing them from dividing. For stomach cancer, patients usually receive chemotherapy through an injection or take it as a pill. This allows the drugs to enter the bloodstream and target cancer cells throughout the body. Chemotherapy may be used in these ways:


  • Before surgery to shrink the tumor, making it easier to remove (neoadjuvant treatment)
  • After surgery to kill any remaining cancer cells (adjuvant treatment)
  • As the main treatment for cancer that has metastasized or cannot be removed by surgery

Radiation Therapy for Stomach Cancer

Radiation therapy uses high-energy rays or particles to kill cancer cells in a specific location in the body. Patients whose treatment plan includes radiation may receive it: 

  • Along with chemotherapy before surgery to try to shrink the cancer and make it easier to remove
  • After surgery to help eliminate any cancer cells that were not removed during the procedure (chemoradiation).
  • To slow cancer growth and ease symptoms, such as pain, bleeding, or eating problems, when surgery isn't an option.

Targeted Therapy for Stomach Cancer

Targeted therapy uses drugs or other substances to find and attack specific cancer cells. Doctors may suggest tests to identify gene mutations (biomarkers) linked to stomach cancer. These tests help predict how well you will respond to certain targeted therapies.

Immunotherapy for Stomach Cancer

Immunotherapy boosts your immune system's ability to fight cancer. Your doctor may recommend biomarker testing to determine which immunotherapy drugs could be most effective for you. Immune checkpoint inhibitors are a type of immunotherapy used for stomach cancer and may be combined with other treatments like chemotherapy and targeted therapy.

Nutritional Needs For Patients Undergoing Treatment for Stomach Cancer

Stomach cancer can make it difficult to eat and digest food. However, proper nutrition is essential to treatment and recovery. At Compass Oncology, our registered dietitian and oncology nutritional services help our patients undergoing stomach cancer treatment understand how to maintain nutrition during treatments and stay strong. 

Some patients may receive nutrition through an IV (intravenous) until they can eat on their own. The oncologist and dietitian will discuss whether this is needed and for how long.

The Latest Stomach Cancer Treatment Options Available in Portland-Vancouver

If you or a loved one was recently diagnosed with GI cancer, such as stomach cancer, the GI oncologists at Compass Oncology are here to help you navigate your cancer treatment journey. We offer patient-centered care using the latest treatments for stomach cancer, with personalized plans tailored to your needs. Our cancer centers are conveniently located throughout the Portland and Vancouver metro area.

Find a Compass Location Near You